PentOS OI™ Sponge | 100% Allograft Compressible Bone Matrix
PentOS OI™ Sponge is made of cancellous and demineralized bone and is available as blocks. Proven to form bone. Every time. It’s that simple!
- Missing laterals
- Gutter defects with screw fixation
All PentOS OI™ allografts must demonstrate all five elements of bone formation before they are released for use.
1. New bone
New bone is the final step in the maturation of the product.
2. Bone marrow
The presence of bone marrow indicates the ability of the product to differentiate into osteoblasts, chondrocytes, cartilage and new bone.
Osteocytes are derived from osteoblasts, or bone forming cells, and are essentially osteoblasts surrounded by the products they secreted.
Cartilage is replaced by bone during ossification in the higher vertebrates. It is indicative that the bone formation is forthcoming.
A Chondrocyte is a unique cell type in articular cartilage tissue and is essential for cartilage formation and functionality. It arises from mesenchymal stem cells.
Post sterilization in-vivo testing on each lot must demonstrate the presence of new bone, bone marrow, osteocytes, cartilage and chondrocytes within 28 days in an athymic rat model otherwise we don’t call it PentOS OI™.
In-vitro tests of PentOS OI™ have demonstrated native levels of BMP-2 up to 19 times the native levels in the control
- Osteoinductive & Osteoconductive
- Hydrates in minutes
- Contours with the defect
- 5 year shelf life at ambient storage
PentOS OI™ Sponge is available in sponge-blocks of:
- 10 mm³
- 12 mm³