Neomem® ECM

Tissue augmentation | Xenograft | Resorbable
Processed porcine mesothelial tissue in sheet form.







Neomem® ECM | Processed porcine mesothelial tissue in sheet form

Neomem® ECM is an extracellular matrix in sheet form with a combination of strength and tissue regeneration properties with minimal antigens. Because Neomem® ECM is more than just collagen, the extra proteins support soft tissue healing and remodeling into natural tissue as the matrix is absorbed.

The Extracellular Matrix (ECM) is a three-dimensional network of extracellular macromolecules, such as collagen, enzymes, and glycoproteins.¹ ECM has been found to support regrowth and healing of tissue.²

Neomem ECM maintains it’s desirable structural characteristics for cellular proliferation, ideal for the following applications:

  • Guided tissue regeneration procedures in periodontal defects
  • Augmentation around implants
  • Provides architecture and protection for bone regeneration and soft tissue aesthetics
  • Alveolar ridge reconstruction for prosthetic treatment



1. David M Hoganson, Gwen E Owens, Elisabeth M O’Doherty, Chris M Bowley, Scott M Goldman, Dina O Harilal, Craig M Neville, Russell T Kronengold, Joseph P Vacanti. Preserved extracellular matrix components and retained biological activity in decellularized porcine mesothelium. Biomaterials. 2010 (27): 6934-40. | 2. Huleihel L, Hussey GS, Naranjo JD, Zhang L, Dziki JL, Turner NJ, Stolz DB, Badylak SF (June 2016). “Matrix-bound nanovesicles within ECM bioscaffolds”. Science Advances. 2 (6): e1600502. Bibcode:2016SciA....2E0502H. doi:10.1126/sciadv.1600502. PMC 4928894. PMID 27386584. “Pitt researchers solve mystery on how regenerative medicine works”. EurekAlert!. Retrieved 2017-03-01.




Biologic characteristics

Cytokines retained in preparation include:

  • Vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF)and transforming growth factor beta (TGF-beta)
  • Levels of VEGF and TGF-beta in Neomem ECM shown to be higher than those found in decellularized small intestinal submucosa (SIS)*


Natural structure preserved

Techniques used for processing and sterilization of the ECM maintains its desirable structural characteristics for cellular proliferation throughout the membrane.


Excellent handling characteristics

  • Drapes easily to surgical site without adhering to itself
  • Sheet form ECM have natural elasticity charateristics


3 year shelf life from date of sterilization

Resorption time: 6 months



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Neomem® ECM is available in membranes of:

  • 15x20 mm
  • 20x30 mm
  • 30x40 mm
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