Accell contains BMPs and growth factors with DBM to accelerate the body’s healing response. In nature, these elements work together as part of the natural bone formation process:
Growth factors (TGF-ß and IGF-1) recruit stem cells to the surgical site. TGF-ß also stimulates the stem cells to replicate, creating the cellular foundation for new bone.
VEG-F stimulates the formation of new blood vessels, increasing blood flow to the site. BMP-2, BMP-4 and BMP-7 transform stem cells into osteoblasts (bone forming cells). FGF and PDGF promote replication of stem cells and osteoblasts. As the osteoblasts form, they organize themselves to create new bone.
Accell Connexus® is a next generation Demineralized Bone Matrix (DBM)-based bone grafting product. In addition to standard DBM, Accell Connexus® contains patented Accell® Bone Matrix (ABM).
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