OrthoBlast II, DBM and Cancellous Bone in a Reverse Phase Medium

OrthoBlast II, the 2-in1 bone graft solution. Combining osteoinductive and osteoconductive elements in a proprietary, reverse phase medium, OrthoBlast® II is a powerful choice for bone grafting. Available in both putty and paste, it contains demineralized bone matrix (DBM) to stimulate new bone growth, and cancellous bone to support bone formation – plus a unique, temperature-responsive medium that facilitates both handling and graft containment.

OrthoBlast II features

• DBM contains the full complex of bone morphogenetic proteins (BMPs) that provide the osteoinductive signal to form new bone.

• Each lot of DBM is tested for osteoinductive potential in a quantitative in vitro assay for its ability to stimulate new bone formation.

• Cancellous bone supplies an osteoconductive scaffold facilitating the attachment of osteogenic precursor cells.

• OrthoBlast II can easily be packed and molded into any defect.

• Due to poloxamer Reverse Phase Medium, OrthoBlast II is highly malleable at room temperature, resists irrigation, and thickens at body temperature for superior containment at the surgical site.

• Delivered sterile in a vial or syringe, OrthoBlast II putty or paste is ready-to-use with no refrigeration, thawing or premixing required.

Available ready to use in a putty (5.0 and 10.0 cc vials) or paste (1.0, 3.0 and 8.0 cc syringes)

OrthoBlast II Clinical Applications

OrthoBlast II is designed to promote natural bone formation by stimulating the proliferation and transformation of mesenchymal cells to osteoblasts. OrthoBlast II can be used in any area where bone formation is desired, including:

• Autograft supplementation

• Osseous deficits

• Autograft backfill

• Spinal fusion (with appropriate fixation)

• Inlay/onlay graft interface (non-structura