MBCP™... For
balanced bone regeneration.
Using the mineral building blocks naturally found in human
bone, MBCP goes a step beyond the realm
of everyday hydroxyapatite (HA) and tricalcium phosphate
(TCP) with its unique combination of micro and macroporosity
technology.
The MBCP key to balanced bone regeneration is its unique
ratio between micro and macro porosity and its unique ratio
between HA and ß-TCP.
40% ß-TCP – calcium
and phosphate ion release 60% HA – scaffold
effect for osteoblastic activity
Microporosity (pores <10µm)
allows the diffusion of biological fluids, by the capillary
action, into the three-dimensional matrix. Inside the fine
pores
of the matrix, biological fluids dissolve ß-TCP producing calcium
phosphate ions that are released back into the biological fluids. This saturation
of ions
leads to precipitation of apatite crystal identical to that of the natural bone
minerals. Shortly afterwards, this process creates a surface that promotes bone
cell adhesion.
Macroporosity (300
to 600µm) promote a deep invasion of osteogenic cells
by osteoconduction. Through the same resorption and formation
cycle as the natural
bone remodeling process, new bone increases progressively at
the expense of the MBCP.
MBCP Gel is composed of rounded biphasic calcium
phosphate granules
in hydrophilic polymer solution.
